ACC foes match up when the SMU Mustangs (6-3) and the Boston College Eagles (1-8) square off on Saturday, November 8, 2025 at Alumni Stadium (Chestnut Hill, MA). The contest will be broadcast on ACC Network, with the kickoff at 12 p.m. ET. Below, we analyze BetMGM Sportsbook’s lines around SMU vs. Boston College odds, and make our expert college football picks and predictions.
The Mustangs head into this matchup after a 26-20 win over the Miami (FL) Hurricanes in their most recent game. The Eagles’ last game was a 25-10 loss to the Notre Dame Fighting Irish. Kevin Jennings threw for 365 yards, with one touchdown and no interceptions on 29-of-44 passing (65.9%) for the Mustangs in that matchup against the Hurricanes. He also added eight carries for -8 yards and one rushing touchdown. Tomarion Harden rushed for 27 yards on eight carries (3.4 yards per carry) and one touchdown, adding two receptions for 15 yards. Jordan Hudson led the receiving charge against the Hurricanes, catching 11 passes for 136 yards.
Grayson James’ performance for the Eagles against the Fighting Irish included 25-of-37 passing for 240 yards, one touchdown and two interceptions. Turbo Richard carried the ball 16 times for 26 yards. He caught four passes for nine yards. Lewis Bond recorded 92 yards through the air after eight catches (on 12 targets).
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SMU vs. Boston College odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 10:25 p.m.
- Moneyline (ML): SMU -431 (Bet $431 to win $100) | Boston College +331 (Bet $100 to win $331)
- Against the spread (ATS): SMU -10.5 (-111) | Boston College +10.5 (-110)
- Over/Under (O/U): 54.5 (O: -110 | U: -110)
How to make SMU vs. Boston College picks
Prediction
SMU 34, Boston College 19
Moneyline
- Moneyline pick: SMU -431
- SMU has compiled a 3-2 record in games it was favored on the moneyline (winning 60% of those games).
- The Mustangs have played in three games as a moneyline favorite with odds of -431 or shorter and won them all.
- Boston College has been the underdog in six games this season, and it has failed to win any of those contests.
- The Eagles have not won as an underdog of +331 or more on the moneyline this season in three such games.
Against the spread
- ATS pick: SMU -10.5
- The Mustangs have covered the spread three times in eight games.
- SMU has won once ATS (1-2) as a 10.5-point or higher favorite this season.
- The Eagles are 4-5-0 against the spread this year.
- As a 10.5-point underdog or greater, Boston College has two wins ATS (2-1).
Over/Under
- O/U pick: Under 54.5 points
- Mustangs games this season have gone over this contest’s total of 54.5 points three times.
- The Eagles have combined with their opponent to score more than 54.5 points in five of nine games this season.
- The teams combine to score 55.7 points per game, 1.2 more points than this matchup’s over/under.
- These two teams give up a combined 54.5 points per game, the same as this contest’s total.
- The average point total in Mustangs outings this year is 57, 2.5 more points than this game’s over/under.
- Eagles games this season have had an average of 53 points, 1.5 fewer points than this game’s point total.
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